1 |
METABOLISM |
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01:01 |
amino-acid metabolism |
01:01:01 |
amino-acid biosynthesis |
01.01.01.01 |
assimilation of ammonia, biosynthesis of the glutamate family |
01.01.01.03 |
urea cycle, biosynthesis of polyamines and creatine |
01.01.01.05 |
assimilatory reduction of sulfur and biosynthesis of the serine family |
01.01.01.07 |
biosynthesis of the aspartate family |
01.01.01.09 |
biosynthesis of lysin |
01.01.01.09.01 |
diaminopimelin acid pathway |
01.01.01.09.03 |
aminoadipic acid pathway |
01.01.01.11 |
biosynthesis of the aromatic family |
01.01.01.13 |
biosynthesis of histidine |
01.01.01.15 |
biosynthesis of pyruvate family and D-alanine |
01:01:04 |
regulation of amino-acid metabolism |
01:01:07 |
amino-acid transport |
01:01:10 |
amino-acid degradation (catabolism) |
01.01.10.01 |
degradation of amino-acids of the glutamate-group |
01.01.10.03 |
degradation of amino-acids of the aspartate-group |
01.01.10.05 |
degradation of amino-acids of the cysteine- aromatic-group |
01.01.10.07 |
degradation of amino-acids of the hydroxyaminoacid-group |
01.01.10.09 |
degradation of amino-acids of the alanine-D-Aminoacid-group |
01.01.99 |
other amino-acid metabolism activities |
01:02 |
nitrogen and sulphur metabolism |
01:02:01 |
nitrogen and sulphur utilization |
01:02:04 |
regulation of nitrogen and sulphur utilization |
01:02:07 |
nitrogen and sulphur transport |
01.02.99 |
other nitrogen and sulphur metabolism activities |
01:03 |
nucleotide metabolism |
01:03:01 |
purine-ribonucleotide metabolism |
01:03:04 |
pyrimidine-ribonucleotide metabolism |
01:03:07 |
deoxyribonucleotide metabolism |
01:03:10 |
metabolism of cyclic and unusual nucleotides |
01:03:13 |
regulation of nucleotide metabolism |
01:03:16 |
polynucleotide degradation |
01.03.16.01 |
RNA degradation |
01.03.16.03 |
DNA degradation |
01:03:19 |
nucleotide transport |
01.03.99 |
other nucleotide-metabolism activities |
01:04 |
phosphate metabolism |
01:04:01 |
phosphate utilization |
01:04:04 |
regulation of phosphate utilization |
01:04:07 |
phosphate transport |
01.04.99 |
other phosphate metabolism activities |
01:05 |
C-compound and carbohydrate metabolism |
01:05:01 |
C-compound and carbohydrate utilization |
01.05.01.01 |
C-compound, carbohydrate catabolism |
01.05.01.01.01 |
sugar, glucoside, polyol and carboxylate catabolism |
01.05.01.01.03 |
C-2 compound, organic acid and fatty acid catabolism |
01.05.01.01.05 |
C-1 compound catabolism |
01.05.01.01.05.01 |
serine-isocitrate lyase pathway |
01.05.01.01.05.03 |
ribulose-monophosphate cycle |
01.05.01.01.07 |
aliphatic hydrocarbon catabolism |
01.05.01.01.09 |
aerobic aromate catabolism |
01.05.01.01.09.01 |
ortho-cleavage |
01.05.01.01.09.03 |
meta-cleavage |
01.05.01.01.11 |
anaerobic aromate catabolism |
01.05.01.03 |
C-compound, carbohydrate anabolism |
01.05.01.03.01 |
polysaccharide biosynthesis |
01.05.01.03.03 |
aminosaccharide biosynthesis |
01.05.01.05 |
autotrophic CO2-fixation |
01.05.01.05.01 |
Calvin cycle (Empty, instead under 02.30.02) |
01.05.01.05.03 |
reductive TCA cycle |
01.05.01.05.05 |
hydroxypropionate pathway |
01.05.01.05.07 |
acetyl-CoA pathway |
01:05:04 |
regulation of C-compound and carbohydrate utilization |
01:05:07 |
C-compound, carbohydrate transport |
01.05.99 |
other carbohydrate metabolism activities |
01:06 |
lipid, fatty-acid and isoprenoid metabolism |
01:06:01 |
lipid, fatty-acid and isoprenoid biosynthesis |
01.06.01.01 |
phospholipid biosynthesis |
01.06.01.03 |
glycolipid biosynthesis |
01.06.01.05 |
fatty acid biosynthesis |
01.06.01.07 |
isoprenoid biosynthesis |
01.06.01.07.01 |
hemiterpenes biosynthesis |
01.06.01.07.03 |
monoterpenes biosynthesis |
01.06.01.07.05 |
sesquiterpenes biosynthesis |
01.06.01.07.07 |
diterpenes biosynthesis |
01.06.01.07.09 |
triterpenes biosynthesis |
01.06.01.07.11 |
tetracyclic and pentacyclic triterpenes (steroids and hopanoids) biosynthesis |
01.06.01.07.13 |
tetraterpenes (carotinoids) biosynthesis |
01.06.01.07.15 |
polyterpenes biosynthesis |
01:06:04 |
breakdown of lipids, fatty acids and isoprenoids |
01:06:07 |
lipid, fatty-acid and isoprenoid utilization |
01:06:10 |
regulation of lipid, fatty-acid and isoprenoid biosynthesis |
01:06:13 |
lipid and fatty-acid transport |
01:06:16 |
lipid and fatty-acid binding |
01.06.99 |
other lipid, fatty-acid and isoprenoid metabolism activities |
01:07 |
metabolism of vitamins, cofactors, and prosthetic groups |
01:07:01 |
biosynthesis of vitamins, cofactors, and prosthetic groups |
01:07:04 |
utilization of vitamins, cofactors, and prosthetic groups |
01:07:07 |
regulation of vitamins, cofactors, and prosthetic groups |
01:07:10 |
transport of vitamins, cofactors, and prosthetic groups |
01.07.99 |
other vitamin, cofactor, and prosthetic group activities |
01:20 |
secondary metabolism |
01:20:01 |
metabolism of primary metabolic sugars derivatives |
01.20.01.01 |
biosynthesis of secondary monosaccharides |
01.20.01.03 |
biosynthesis of sugar carboxylic acids |
01.20.01.05 |
biosynthesis of sugar alcohols |
01.20.01.07 |
biosynthesis of glycosides |
01.20.01.09 |
biosynthesis of aminoglycoside antibiotics |
01.20.01.99 |
other biosynthesis of primary metabolic sugars derivatives |
01:20:03 |
biosynthesis of derivatives of intermediates of glucose degradation |
01:20:05 |
biosynthesis of acetic acid derivatives |
01.20.05.01 |
biosynthesis of acetoacetate, acetone, hydroxybutyric acid |
01.20.05.03 |
biosynthesis of alkanes, alkenes, alkanals, alkanols |
01.20.05.05 |
biosynthesis of fatty acid esters |
01.20.05.07 |
biosynthesis of acetylenes |
01.20.05.09 |
biosynthesis of eicosanoids |
01.20.05.11 |
biosynthesis of polyketides |
01.20.05.99 |
other biosynthesis of acetic acid derivatives |
01:20:07 |
biosynthesis of propionic acid derivatives |
01:20:09 |
biosynthesis of derivatives of intermediates of the TCA and glyoxylate pathway |
01:20:13 |
biosynthesis of derivatives of homoisopentenyl pyrophosphate |
01:20:15 |
biosynthesis of derivatives of dehydroquinic acid, shikimic acid and chorismic acid |
01.20.15.01 |
biosynthesis of naphthoquinone, anthraquinone |
01.20.15.03 |
biosynthesis of ubiquinone |
01.20.15.99 |
other biosynthesis of derivatives of dehydroquinic acid, shikimic acid and chorismic acid |
01:20:17 |
biosynthesis of secondary products derived from primary amino acids |
01.20.17.01 |
biosynthesis of nonprotein amino acids |
01.20.17.03 |
biosynthesis of amines |
01.20.17.05 |
biosynthesis of cyanogenic glycosides |
01.20.17.07 |
biosynthesis of glycosinolates and derivatives |
01.20.17.09 |
biosynthesis of alkaloids |
01:20:19 |
biosynthesis of secondary products derived from glycine, L-serine and L-alanine |
01.20.19.01 |
biosynthesis of porphyrins |
01.20.19.03 |
biosynthesis of tetrapyrrols |
01.20.19.05 |
biosynthesis of cobalamins |
01.20.19.99 |
other biosynthesis of secondary products derived from glycine, L-serine and L-alanine |
01:20:21 |
biosynthesis of sulfuric acid and L-cysteine derivatives |
01:20:23 |
biosynthesis of L-Methionine derived secondary products |
01:20:25 |
biosynthesis of secondary products originating from L-valin, L-leucin and L-isoleucin |
01:20:27 |
biosynthesis of secondary products build from L-aspartic acid and L-threonine |
01:20:29 |
biosynthesis of secondary products derived from L-glutamic acid, L-proline and L-ornithine |
01:20:31 |
biosynthesis of secondary products derived from L-lysine, L-arginine and L-histidine |
01:20:33 |
biosynthesis of secondary products build from L-tryptophan |
01:20:35 |
biosynthesis of secondary products derived from L-phenylalanine and L-tyrosine (Phenylpropanoids) |
01.20.35.01 |
biosynthesis of melanins |
01.20.35.03 |
biosynthesis of lignins |
01.20.35.05 |
biosynthesis of stilbenes, flavonoids |
01.20.35.07 |
biosynthesis of coumarins |
01.20.35.09 |
biosynthesis of cinnamic acids |
01.20.35.99 |
other biosynthesis of phenylpropanoids |
01:20:37 |
biosynthesis of peptide derived compounds |
01.20.37.01 |
biosynthesis of thioredoxin, glutaredoxin, glutathion |
01.20.37.03 |
biosynthesis of peptide antibiotics |
01.20.37.05 |
biosynthesis of beta-lactams |
01.20.37.99 |
other biosynthesis of peptide derived compounds |
01.20.99 |
other secondary metabolism activities |
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2 |
ENERGY |
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02:01 |
glycolysis and gluconeogenesis |
02:01:01 |
glycolysis methylglyoxal bypass |
02:05 |
Entner-Doudoroff pathway |
02:07 |
pentose-phosphate pathway |
02:07:01 |
pentose-phosphate pathway oxidative branch |
02:07:03 |
pentose-phosphate pathway non oxidative branch |
02:09 |
anaplerotic reactions |
02:10 |
tricarboxylic-acid pathway |
02:11 |
electron transport and membrane-associated energy conservation |
02:11:01 |
electron transport proteins |
02:11:03 |
ATP synthesis proteins |
02:11:05 |
accessory proteins of electron transport and membrane-associated energy conservation |
02.11.99 |
other electron transport and membrane-associated energy conservation proteins |
02:13 |
respiration |
02:13:01 |
anaerobic respiration |
02:13:03 |
aerobic respiration |
02:16 |
fermentation |
02:16:01 |
alcohol fermentation |
02.16.01.01 |
bacterial type ethanol fermentation |
02.16.01.99 |
other ethanol fermentation |
02:16:03 |
lactate fermentation |
02.16.03.01 |
homofermentative pathway |
02.16.03.03 |
heterofermentative pathway and fermentaton of other saccharides |
02.16.03.05 |
bifidum pathway |
02.16.03.07 |
malo-lactate fermentation |
02:16:05 |
butyrate and butanol-acetone fermentation |
02:16:07 |
ethanol-acetate fermentation |
02:16:09 |
mixed acid and butanediol fermentation |
02:16:11 |
propionate fermentation |
02.16.11.01 |
acrylate pathway |
02.16.11.03 |
succinate-propionate pathway |
02:16:13 |
acetate fermentation |
02:16:15 |
methane fermentation |
02:16:17 |
fermentation of nitrogenous compounds |
02.16.17.01 |
single amino acid fermentations |
02.16.17.03 |
stickland reactions |
02.16.17.05 |
fermentation of heterocyclic compounds |
02.16.99 |
other fermentation proteins |
02:17 |
chemolithotrophie (sulfide, nitrogenous compounds) |
02:19 |
metabolism of energy reserves (glycogen, trehalose) |
02:22 |
glyoxylate cycle |
02:25 |
oxidation of fatty acids |
02:30 |
photosynthesis |
02:30:01 |
electron transport proteins of photosynthesis |
02.30.01.01 |
Photosystem I |
02.30.01.01.01 |
Reaction center complex |
02.30.01.01.02 |
LHC I |
02.30.01.02 |
Photosystem II |
02.30.01.02.01 |
Reaction center complex |
02.30.01.02.02 |
LHC II |
02.30.01.03 |
Cytochrome b6f complex |
02.30.01.04 |
ATPase complex |
02:30:02 |
Photosynthetic carbon metabolism |
02.30.02.01 |
Rubisco |
02.30.02.02 |
Calvin cycle |
02.30.02.03 |
Starch biosynthesis |
02.30.02.04 |
Sucrose biosynthesis |
02.30.02.05 |
Photorespiration |
02.30.02.05.01 |
Photorespiratory C-cycle |
02.30.02.05.02 |
Photorespiratory N-cycle |
02:30:03 |
accessory proteins of photosynthetic electron transport |
02.99 |
other energy generation activities |
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3 |
CELL GROWTH, CELL DIVISION AND DNA SYNTHESIS |
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03:01 |
cell growth |
03:04 |
budding, cell polarity and filament formation |
03:07 |
pheromone response, mating-type determination, sex-specific proteins |
03:10 |
sporulation and germination |
03:13 |
meiosis |
03:16 |
DNA synthesis and replication |
03:19 |
recombination and DNA repair |
03:22 |
cell cycle control and mitosis |
03:22:01 |
cell cycle check point proteins |
03:25 |
cytokinesis |
03:26 |
growth regulators |
03.99 |
other cell growth, cell division and DNA synthesis activities |
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4 |
TRANSCRIPTION |
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04:01 |
rRNA transcription |
04:01:01 |
rRNA synthesis |
04:01:04 |
rRNA processing |
04.01.99 |
other rRNA-transcription activities |
04:03 |
tRNA transcription |
04:03:01 |
tRNA synthesis |
04:03:03 |
tRNA processing |
04:03:06 |
tRNA modification |
04.03.99 |
other tRNA-transcription activities |
04:05 |
mRNA transcrition |
04:05:01 |
mRNA synthesis |
04.05.01.01 |
general transcription activities |
04.05.01.04 |
transcriptional control |
04.05.01.07 |
chromatin modification |
04:05:03 |
mRNA processing (splicing) |
04:05:05 |
mRNA processing (5'-, 3'-end processing, mRNA degradation) |
04.05.99 |
other mRNA-transcription activities |
04:07 |
RNA transport |
04.99 |
other transcription activities |
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5 |
PROTEIN SYNTHESIS |
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05:01 |
ribosomal proteins |
05:04 |
translation (initiation, elongation and termination) |
05:07 |
translational control |
05:10 |
tRNA-synthetases |
05.99 |
other protein-synthesis activities |
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6 |
PROTEIN DESTINATION |
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06:01 |
protein folding and stabilization |
06:04 |
protein targeting, sorting and translocation |
06:07 |
protein modification (glycolsylation, acylation, myristylation, palmitylation, farnesylation and processing) |
06:10 |
assembly of protein complexes |
06:13 |
proteolysis |
06:13:01 |
cytoplasmic degradation |
06:13:04 |
lysosomal and vacuolar degradation |
06:13:07 |
other proteolytic degradation |
06:20 |
storage proteins |
06.99 |
other protein-destination activities |
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7 |
TRANSPORT FACILITATION |
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07:01 |
ion channels |
07:04 |
ion transporters |
07:04:01 |
metal ion transporters (Cu, Fe, etc.) |
07:04:04 |
other cation transporters (Na ,K ,Ca ,NH4 ,etc.) |
07:04:07 |
anion transporters (Cl, SO4, PO4, etc.) |
07:07 |
sugar and carbohydrate transporters |
07:07:01 |
phosphotransferase systems |
07:10 |
amino-acid transporters |
07:11 |
peptide-transporters |
07:13 |
lipid transporters |
07:16 |
purine and pyrimidine transporters |
07:19 |
allantoin and allantoate transporters |
07:22 |
transport ATPases |
07:25 |
ABC transporters |
07:28 |
drug transporters |
07:30 |
protein secretion systems |
07:30:03 |
Type I protein secretion system |
07:30:05 |
Type II protein secretion system |
07:30:07 |
Type III protein secretion system |
07:30:09 |
Type IV protein secretion system |
07:30:11 |
other protein secretion systems |
07.99 |
other transport facilitators |
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8 |
INTRACELLULAR TRANSPORT |
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08:01 |
nuclear transport |
08:02 |
chloroplast transport |
08:04 |
mitochondrial transport |
08:07 |
vesicular transport (Golgi network, etc.) |
08:10 |
peroxisomal transport |
08:13 |
vacuolar transport |
08:16 |
extracellular transport (secretion) |
08:19 |
cellular import |
08:22 |
cytoskeleton-dependent transport |
08.99 |
other intracellular-transport activities |
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9 |
CELLULAR BIOGENESIS (proteins are not localized to the corresponding organelle) |
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09:01 |
biogenesis of cell wall (cell envelope) |
09:02 |
biogenesis of plasma membrane |
09:03 |
biogenesis of cytoplasm |
09:04 |
biogenesis of cytoskeleton |
09:07 |
biogenesis of endoplasmatic reticulum |
09:08 |
biogenesis of Golgi |
09:09 |
biogenesis of intracellular transport vesicles |
09:10 |
nuclear biogenesis |
09:13 |
biogenesis of chromosome structure |
09:16 |
mitochondrial biogenesis |
09:19 |
peroxisomal biogenesis |
09:22 |
endosomal biogenesis |
09:25 |
vacuolar and lysosomal biogenesis |
09:26 |
chloroplast biogenesis |
09:27 |
biogenesis of outer membrane |
09:28 |
biogenesis of periplasmic space |
09:29 |
biogenesis of inner membrane |
09:30 |
biogenesis of flagellae |
09:33 |
biogenesis of pili |
09.99 |
other cellular biogenesis activities |
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10 |
CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION |
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10:00 |
intercellular communication |
10:00:01 |
pheromones |
10:00:03 |
hormones |
10:00:05 |
cytokines |
10:01 |
intracellular communication |
10:01:01 |
unspecified signal transduction |
10.01.01.01 |
receptor proteins |
10.01.01.03 |
second messenger formation |
10.01.01.05 |
mediator proteins |
10.01.01.07 |
G-proteins |
10.01.01.09 |
regulation of G-protein activity |
10.01.01.11 |
key kinases |
10.01.01.13 |
key phosphatases |
10.01.01.15 |
two-component signal transduction |
10.01.01.99 |
other unspecified signal transduction activities |
10:01:05 |
morphogenesis |
10.01.05.01 |
receptor proteins |
10.01.05.03 |
second messenger formation |
10.01.05.07 |
G-proteins |
10.01.05.09 |
regulation of G-protein activity |
10.01.05.11 |
key kinases |
10.01.05.13 |
key phosphatases |
10.01.05.99 |
other morphogenetic activities |
10:01:10 |
osmosensing |
10.01.10.01 |
receptor proteins |
10.01.10.05 |
mediator proteins |
10.01.10.11 |
key kinases |
10.01.10.13 |
key phosphatases |
10.01.10.99 |
other osmosensing activities |
10:01:15 |
nutritional response pathway |
10.01.15.01 |
receptor proteins |
10.01.15.03 |
second messenger formation |
10.01.15.05 |
mediator proteins |
10.01.15.07 |
G-proteins |
10.01.15.09 |
regulation of G-protein activity |
10.01.15.11 |
key kinases |
10.01.15.13 |
key phosphatases |
10.01.15.99 |
other nutritional-response activities |
10:01:20 |
pheromone response generation |
10.01.20.01 |
receptor proteins |
10.01.20.07 |
G-proteins |
10.01.20.09 |
regulation of G-protein activity |
10.01.20.11 |
key kinases |
10.01.20.13 |
key phosphatases |
10.01.20.99 |
other pheromone response activities |
10.01.99 |
other signal-transduction activities |
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11 |
CELL RESCUE, DEFENSE, CELL DEATH AND AGEING |
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11:01 |
stress response |
11:04 |
DNA repair (direct repair, base excision repair and nucleotide excision repair) |
11:05 |
Disease, virulence and defense |
11:05:01 |
resistance proteins |
11:05:03 |
defense related proteins |
11:05:05 |
virulence, disease factors |
11.05.05.01 |
Toxins |
11.05.05.03 |
Bacteriocins |
11.05.05.05 |
Invasins |
11.05.05.07 |
Adhaesins |
11.05.05.09 |
Capsule |
11.05.05.11 |
DNA-Restriction and modification |
11.05.05.13 |
major antigenic determinants |
11.05.05.99 |
other virulence, disease factors |
11.05.99 |
other desease and defense related proteins |
11:07 |
detoxificaton |
11:07:01 |
detoxification involving cytochrome P450 |
11:07:03 |
detoxification by modification |
11:07:05 |
detoxification by export |
11.07.99 |
other detoxification |
11:10 |
cell death |
11:11 |
ageing |
11:13 |
degradation of exogenous polynucleotides |
11:15 |
degradation of exogenous proteins |
11:17 |
degradation of exogenous polysaccharides |
11:19 |
degradation of exogenous ester compounds |
11.99 |
other cell rescue activities |
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13 |
IONIC HOMEOSTASIS |
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13:01 |
homeostasis of metal ions |
13:04 |
homeostasis of other ions |
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30 |
CELLULAR ORGANIZATION (proteins are localized to the corresponding organelle) |
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30.01 |
organization of cell wall |
30.02 |
organization of plasma membrane |
30.03 |
organization of cytoplasm |
30.04 |
organization of cytoskeleton |
30.05 |
organization of centrosome |
30.07 |
organization of endoplasmatic reticulum |
30.08 |
organization of Golgi |
30.09 |
organization of intracellular transport vesicles |
30.10 |
nuclear organization |
30.13 |
organization of chromosome structure |
30.16 |
mitochondrial organization |
30.19 |
peroxisomal organization |
30.22 |
endosomal organization |
30.25 |
vacuolar and lysosomal organization |
30.26 |
chloroplast organization |
30.27 |
outer membrane organization |
30.28 |
periplasmatic space organization |
30.29 |
inner membrane organization |
30.30 |
flagellar organization |
30.33 |
pilus organization |
30.90 |
extracellular/secretion proteins |
30.99 |
other cellular organization |
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35 |
MOTILITY |
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35.01 |
chemotaxis |
35.02 |
phototaxis |
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50 |
DEVELOPMENT |
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50.01 |
differentiation of prokaryotes |
50.02 |
development of eukaryotes |
50.02.01 |
fungi |
50.02.02 |
plants |
50.02.03 |
mammals |
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90 |
RETROTRANSPOSONS AND PLASMID PROTEINS |
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90.01 |
LTR retroelements |
90.02 |
non-LTR retroelements |
90.99 |
other retrotransposons and plasmid proteins |
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97 |
ORGANISM SPECIFIC PROTEINS |
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98 |
CLASSIFICATION NOT YET CLEAR-CUT |
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99 |
UNCLASSIFIED PROTEINS |